Palmitoyl Tetrapeptide-7
Also known as: Palmitoyl Tetrapeptide-7, Pal-GQPR, Palmitoyl Tetrapeptide 7
What It Is
A lipid-conjugated 4-amino-acid peptide that forms the anti-inflammatory component of the Matrixyl 3000 peptide complex, paired with Palmitoyl Tripeptide-1.
What It Does
Inhibits the overproduction of interleukins (inflammatory signaling molecules) that break down collagen and elastin during the aging process. Works synergistically with Palmitoyl Tripeptide-1 — one stimulates collagen production, the other prevents its excessive breakdown.
Best For
Benefits
- Anti-inflammatory mechanism that protects existing collagen and elastin from inflammation-driven breakdown
- Synergistic with Palmitoyl Tripeptide-1 — together they cover both collagen production and protection
- Excellent safety profile
When to Be Careful
- Most effective as part of the complete Matrixyl 3000 combination — less studied as a standalone
The Matrixyl 3000 combination (Tripeptide-1 + Tetrapeptide-7) has genuine clinical backing and has become one of the most referenced peptide complexes in anti-aging skincare.
Tetrapeptide-7 isn't the "collagen builder" half — that's Tripeptide-1. Tetrapeptide-7 is the "collagen protector" half, working through anti-inflammatory pathways.
Peptide serum step — morning or evening.
Palmitoyl Tripeptide-1 (essential partner), Hyaluronic Acid, Niacinamide
Very safe peptide with no known irritation concerns.
No overuse reactions associated with this peptide.