Oligopeptide-2
Also known as: Oligopeptide-2, EGF-like Peptide, Epidermal Growth Factor Peptide
What It Is
A short synthetic peptide that mimics the activity of Epidermal Growth Factor (EGF). Used in skincare and hair care for its potential to support cell renewal and follicle activity.
What It Does
May stimulate cell renewal and growth factor signaling pathways. In lash/brow serums, targeted toward supporting the hair follicle growth environment.
Best For
Benefits
- EGF-receptor targeting approach for follicle stimulation
- Short peptide chain — good stability and penetration
When to Be Careful
- EGF-like activity from topical peptides is debated — receptor binding in intact skin is not straightforward
- Often used as a supporting ingredient rather than the primary active
EGF has strong clinical data in wound healing contexts. Cosmetic peptides that mimic EGF activity attract attention for anti-aging and hair growth applications.
Topical EGF peptides do not behave identically to growth factor injections or wound-healing applications. The skin barrier limits penetration, and cosmetic concentrations are lower than research contexts.
As part of a lash/brow serum applied twice daily, or as part of an anti-aging serum in PM routine.
Myristoyl Pentapeptide-17, Biotinoyl Tripeptide-1 in lash/brow context; collagen peptides in anti-aging context
Very rare — generally well tolerated.
Not a known irritant at cosmetic concentrations.